compound introduction
Larotrectinib (Vitrakvi, LOXO-101, ARRY-470) 是一种具有ATP竞争性的、口服给药的 tropomyosin-related kinase (TRK) family receptors 的高度选择性抑制剂。
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LarotrectinibFor
Dangerous GoodsCAS number：1223403-58-4 molecular formula：C21H22F2N6O2
overview
Specs
| Chinese alias | - | ||
| English alias | NYNZQNWKBKUAII-KBXCAEBGSA-N | DB14723 | Q27081513 | ARRY470 | ARRY-470 | ARRY-470; larotrectinib | AS-35231 | Larotrectinib [INN] | larotrectinibum | Vitrakvi | 1223403-58-4 | (S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin -1-yl)pyrazolo[1,5-a]pyrimidin-3 | ||
| CAS number | 1223403-58-4 | molecular formula | C21H22F2N6O2 |
| molecular weight | 428.4 g/mol | Exact mass | - |
| PSA | 86.000 Ų | logp | 1.7 |
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Safety information
pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H302: 吞食有害 H317: 可能引起皮肤过敏反应
Statement of Preventive Measures：
P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。
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