compound introduction
SMIFH2 是一种特定的 formin 抑制剂，可在体外抑制 formin 驱动的肌动蛋白聚合，对于不同形式formin的 IC50 范围为 5 mM 至 15 μM。
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SMIFH2 Formin FH2 Domain Inhibitor
Dangerous GoodsCAS number：340316-62-3 molecular formula：C15H9BrN2O3S
overview
Specs
| Chinese alias | 1-(3-溴苯基)-5-(呋喃-2-基亚甲基)-2-硫代嘧啶-4,6(1H,5H)-二酮 | ||
| English alias | AKOS001651888 | 1-(3-Bromophenyl)-5-(2-furanylmethylene)dihydro-2-thioxo-4,6(1H,5H)-pyrimidinedione | BIM-0040107.P001 | AKOS040745366 | (5E)-1-(3-bromophenyl)-5-(furan-2-ylmethylidene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione | SMIFH2 | (5E)-1-(3-BROMO | ||
| CAS number | 340316-62-3 | molecular formula | C15H9BrN2O3S |
| molecular weight | 377.21 g/mol | Exact mass | 10mM in DMSO |
| PSA | 94.600 Ų | logp | 3.100 |
numbering system
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physicochemical properties
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Safety information
pictogram：
GHS06
Signal word：
Danger
Hazard Statement：
H301: 吞咽会中毒
Statement of Preventive Measures：
P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P330: 漱口 P301+P316: 如果吞咽：立即寻求紧急医疗救助。
WGK Germany：
3
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MSDS
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