Information MDK 24720 (CTLA-4 inhibitor) MDK 24720 (CTLA-4 inhibitor, compound 6b) is an inhibitor of Cytotoxic T-Lymphocyte-Associated protein 4 (CTLA-4, CD152) with IC50 of 50 nM for B7.1–CD28 inhibition. Targets CD152 ; B7.1–CD28 (Cell-free assay) ; 50 nM
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MDK 24720 (CTLA-4 inhibitor)
Dangerous GoodsCAS number:635324-72-0 molecular formula:C21H13F4N5O
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compound introduction
Specs
| Chinese alias | - | ||
| English alias | 2-(4-Fluorophenyl)-6-methyl-4-(3-(trifluoromethyl)phenyl)-1,2-dihydrodipyrazolo[3,4-b:3',4'-d]pyridin-3(6H)-one | B7/CD28 interaction inhibitor 1 | ||
| CAS number | 635324-72-0 | molecular formula | C21H13F4N5O |
| molecular weight | 427.35 g/mol | Exact mass | ≥96% |
| PSA | 63.100 Ų | logp | 4.500 |
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Safety information
Signal word:
Warning
Hazard Statement:
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H302: 吞食有害
Statement of Preventive Measures:
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
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