Indazole-Cl (Ind-Cl) 是一种雌激素受体 (ER)-β 特异性激动剂,具有炎症作用。Indazole-Cl 抑制缺氧诱导的环氧合酶 2 表达降低。Indazole-Cl 抑制 ROS 的产生。Indazole-Cl 还抑制因缺氧而增加的细胞迁移和侵袭。 Indazole-Cl 是血管平滑肌细胞 (VSMC) 缺氧诱导炎症的有效抑制剂。
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3-chloro-2-(4-hydroxyphenyl)-2H-indazol-5-ol
Dangerous GoodsCAS number:848142-62-1 molecular formula:C13H9ClN2O2
overview
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Specs
| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 848142-62-1 | molecular formula | C13H9ClN2O2 |
| molecular weight | 260.68 g/mol | Exact mass | ≥98% |
| PSA | 58.300 Ų | logp | 3.500 |
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Safety information
pictogram:
GHS07
Signal word:
Warning
Hazard Statement:
H361: 怀疑破坏生育力或未出生的孩子
Statement of Preventive Measures:
P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P330: 漱口 P301+P317: 如果被吞咽:请寻求医疗帮助。
WGK Germany:
3
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