Dapagliflozin

Dangerous Goods

CAS number：461432-26-8 molecular formula：C21H25ClO6

overview

Specs

numbering system

physicochemical properties

Safety information

Production methods and uses

MSDS

overview

compound introduction

Dapagliflozin是一种有效的，选择性的hSGLT2抑制剂，EC50为1.1 nM，比作用于hSGLT1选择性高1200倍。Phase 4。A SGLT-2 inhibitor Dapagliflozin is a potent and selective SLC5A2 inhibitor with EC50 of 1.1 nM. It has good permeability across Caco-2 cell membranes and is a substrate for P-glycoprotein (P-gp). Dapagliflozin is not a significant P-gp inhibitor. A SGLT-2 inhibitor

Specs

Chinese alias	-
English alias	BDBM50448923 \| EN300-7407160 \| (2S,3R,4R,5S,6R)-2-[4-chloro-3-(4-ethoxy-benzyl)-phenyl]-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol \| DTXCID101334207 \| (1S)-1,5-anhydro-1-[4-chloro-3-(4-ethoxybenzyl)phenyl]-D-glucitol \| (1S)-1,5-Anhydro-1-C-[4-chloro-3-[
CAS number	461432-26-8	molecular formula	C21H25ClO6
molecular weight	408.87 g/mol	Exact mass	-
PSA	99.400 Å²	logp	2.300

numbering system

No numbering system information yet

physicochemical properties

No physical and chemical property information yet

Safety information

pictogram：

GHS08 , GHS05 , GHS07

Signal word：

Danger

Hazard Statement：

H373: 通过长时间或反复暴露对器官造成损害 H413: 可能对水生生物造成长期的有害影响 H302: 吞食有害 H318: 造成严重的眼睛损伤 H372: 通过长时间或反复暴露对器官造成损害

Statement of Preventive Measures：

P273: 避免释放到环境中。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P330: 漱口 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P301+P317: 如果被吞咽：请寻求医疗帮助。 P305+P354+P338: 如果进入眼睛：立即用水冲洗几分钟。取下隐形眼镜（如果有的话），并且操作简单。