4-甲基伞形酮基β-D-半乳糖吡喃糖苷-6硫酸钠盐用于测定半乳糖6硫酸盐硫酸酯酶的活性。 Product Describtion: 4-Methylumbelliferyl β-D-Galactopyranoside-6-sulfate Sodium Salt is used for the determination of galactose-6-sulphate sulphatase activity. Product Application: 4-Methylumbelliferyl β-D-Galactopyranoside-6-sulfate (sodium salt) (4-MU-Gal-6S) is a fluorogenic substrate used to quantify N-acetylgalactosamine-6-sulphatase (GALNS) activity. 4-MU-Gal-6S is cleaved by GALNS to release the fluorescent moiety 4-MU. 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low ( 1.97-6.72) and high ( 7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM, increasing as pH decreases. It has been used to detect Morquio disease type A, a lysosomal storage disorder in which GALNS is deficient. 4-MU-Gal-6S can be used to assess GALNS activity in a very small blood volume to determine the extent of deficiency.
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4-Methylumbelliferyl β-D-Galactopyranoside-6-sulfate Sodium Salt
Dangerous GoodsCAS number：206443-06-3 molecular formula：C16H17O11S・Na
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Specs
| Chinese alias | - | ||
| English alias | [(2R,3R,4S,5R,6S)-3,4,5-trihydroxy-6-(4-methyl-2-oxochromen-7-yl)oxyoxan-2-yl]methyl sulfate | ||
| CAS number | 206443-06-3 | molecular formula | C16H17O11S・Na |
| molecular weight | 440.35 g/mol | Exact mass | ≥97% |
| PSA | - | logp | - |
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WGK Germany：
3
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