Radafaxine hydrochloride (GW-353162A) is a DAT (dopamine transporter) and NET(norepinephrine transporter) transporters inhibitor, and nAChR family modulator. Radafaxine hydrochloride (GW-353162A) is a potent metabolite of bupropion and selective for inhibiting the reuptake of norepinephrine over dopamine . In Vitro The relatively low potency of Radafaxine hydrochloride (GW-353162A) in blocking DAT and its slow blockade suggests that it is unlikely to have reinforcing effects. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
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Radafaxine hydrochloride
CAS number:106083-71-0(DMSO) molecular formula:C13H19Cl2NO2
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Specs
| Chinese alias | 盐酸雷达法辛 | ||
| English alias | - | ||
| CAS number | 106083-71-0(DMSO) | molecular formula | C13H19Cl2NO2 |
| molecular weight | 292.2 g/mol | Exact mass | 10mM in DMSO |
| PSA | - | logp | - |
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physicochemical properties
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Safety information
pictogram:
GHS07
Signal word:
Warning
Hazard Statement:
H319: 引起严重眼睛刺激
Statement of Preventive Measures:
P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P337+P317: 如果眼睛刺激持续:寻求医疗帮助。
WGK Germany:
3
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