CAS number：545380-34-5 molecular formula：C22H20N4O
QNZ (EVP4593)有效抑制NF-κB激活和TNF-α产生，IC50分别为11 nM和7 nM。An inhibitor of the transcription factor NFκB. QNZ (EVP4593) 强抑制 NF-κB 转录激活和 TNF-α 产生，IC50 分别为 11 和 7 nM。QNZ (EVP4593) 是一种保护神经的钙池操纵的钙通道 (SOC) 抑制剂。 QNZ (EVP4593)有效抑制NF-κB激活和TNF-α产生，在Jurkat T细胞中IC50分别为11 nM和7 nM。 QNZ (EVP4593) shows potent inhibitory activity toward both NF-κB activation and TNF-α production with IC50 of 11 nM and 7 nM, respectively. An inhibitor of the transcription factor NFκB.
| Chinese alias | N4-(4-苯氧基苯乙基)喹唑啉-4,6-二胺 | N4-[2-(4-苯氧基苯基)乙基]-4,6-喹唑啉二胺 | 6-氨基-4-[2-(4-苯氧基苯基)乙氨基]喹唑啉 | ||
| English alias | EVP-4593 | Curator_000005 | N~4~-[2-(4-Phenoxyphenyl)ethyl]quinazoline-4,6-diamine | EVP4593 | GTPL6012 | BCP07901 | DTXSID00333507 | HMS3652J12 | AC-32085 | 4,6-Quinazolinediamine, N4-[2-(4-phenoxyphenyl)ethyl]- | QNZ(EVP4593) | AMY24212 | FT-0661997 | E | ||
| CAS number | 545380-34-5 | molecular formula | C22H20N4O |
| molecular weight | 356.42 g/mol | Exact mass | - |
| PSA | 73.100 Ų | logp | 4.700 |
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