CAS number：1007647-73-5 molecular formula：C22H20ClF3N4O3S
Smurf1-IN-A01 (A01) 是一种泛素连接酶 Smad 泛素化调节因子-1 (Smurf1) 抑制剂，kd 值为 3.664 nM，Smurf1-IN-A01 通过抑制 Smurf1 介导的 Smad1/5 降解来提高 BMP-2 的反应性。 Product Describtion: Smurf1-IN-A01 (A01) is an ubiquitin ligase Smad ubiquitination regulatory factor-1 (Smurf1) inhibitor with a kd of 3.664 nM, which increases BMP-2 responsiveness by inhibiting Smurf1-mediated Smad1/5 degradation.
| Chinese alias | [4-[[4-氯-3-(三氟甲基)苯基] 磺酰基]-1-哌嗪基] [4-(5-甲基-1H-吡唑-1-基)苯基] 甲酮 | ||
| English alias | [4-[[4-Chloro-3-(trifluoromethyl)phenyl]sulfonyl]-1-piperazinyl][4-(5-methyl-1H-pyrazol-1-yl)phenyl]methanone | ||
| CAS number | 1007647-73-5 | molecular formula | C22H20ClF3N4O3S |
| molecular weight | 512.93 g/mol | Exact mass | ≥98%(HPLC) |
| PSA | 83.900 Ų | logp | 3.900 |
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