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Ro 25-6981 Maleate

Dangerous Goods

CAS number:1312991-76-6    molecular formula:C22H29NO2 · C4H4O4

overview

compound introduction

储存在室温下。存放在干燥的条件下。该产品最多可存储12个月。 旋光:[α]/D +15 to +22°, c = 1 in methanol Ro 25-6981 Maleate 是一种有效的、选择性和活性依赖性的 NR2B 亚基特异性 NMDA 受体 拮抗剂。Ro 25-6981 Maleat 具有抗惊厥和抗帕金森病活性。Ro 25-6981 Maleate 具有研究帕金森病(PD)的潜力。 Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months. Ro 25-6981 Maleate is a potent, selective and activity-dependent NR2B subunit specific NMDA receptor antagonist. Ro 25-6981 Maleat shows anticonvulsant and anti-parkinsonian activity. Ro 25-6981 Maleate has the potential for the research of parkinson's disease (PD) Application: Ro 25-6981 maleate salt has been used as a selective N-methyl D-aspartate receptor subtype 2B (NR2B) blocker to study its effects on patch-clamp recordings of N-methyl D-aspartate receptor subtype 2A (NR2A)-containing N-methyl D-aspartate receptor (NMDAR) excitatory postsynaptic currents (EPSCs).

Specs

Chinese alias-
English alias4-[(1R,2S)-3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-methylpropyl]phenol | Ro 25-6981 maleate salt | 1-Piperidinepropanol | α-(4-hydroxyphenyl)-β-methyl-4-(phenylmethyl)- | ( αR,βS)-, (2Z)-2-butenedioate (1:1) | [R-(R*,S*)]-α-(4-Hydroxyphenyl)-β-methyl-4-(ph
CAS number1312991-76-6molecular formulaC22H29NO2 · C4H4O4
molecular weight455.54 g/molExact mass≥98%
PSA43.700 Ųlogp4.200

numbering system

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physicochemical properties

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Safety information

pictogram:
GHS09 , GHS07
Signal word:
警告
Hazard Statement:
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H400: 对水生生物有剧毒
Statement of Preventive Measures:
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。 P273: 避免释放到环境中。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染:用水充分清洗。 P321: 特殊处理(请参阅此标签上的...)。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P304

Production methods and uses

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upstream information

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downstream information

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MSDS

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