CAS number：186097-54-1 molecular formula：C28H39ClN2O5
HCN频道阻止程序；神经元Ih和相关心脏If通道的开放通道阻滞剂。 An HCN Channel blocker; an open channel blocker of neuronal Ih and related cardiac If channels. Application： DK-AH 269 has been used as a hyperpolarization-activated and cyclic nucleotide-gated channel (HCN) antagonist to study its effects on the inhibition of Ih in HCN-deficient hair cells of mice.It has also been used as an HCN blocker to study its effects on action potential firing in the suprachiasmatic nucleus (SCN) neurons
| Chinese alias | cilobradine 盐酸盐 | 西洛雷定盐酸盐 | ||
| English alias | HY-18940A | DTXSID10582024 | DK-AH 269 | 3-[[(3S)-1-[2-(3,4-dimethoxyphenyl)ethyl]piperidin-3-yl]methyl]-7,8-dimethoxy-2,5-dihydro-1H-3-benzazepin-4-one;hydrochloride | DK-AH 269, >=98% (HPLC), solid | 3-({(3S)-1-[2-(3,4-Dimethoxyphenyl)ethyl]piperidin-3- | ||
| CAS number | 186097-54-1 | molecular formula | C28H39ClN2O5 |
| molecular weight | 519.07 g/mol | Exact mass | ≥98% |
| PSA | 60.500 Ų | logp | - |
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