Tyrphostin B44, (+) enantiomer

Dangerous Goods

CAS number：133550-37-5 molecular formula：C18H16N2O3

overview

Specs

numbering system

physicochemical properties

Safety information

Production methods and uses

MSDS

overview

compound introduction

Tyrphostin B44, (+) enantiomer is an inhibitor of epidermal growth factor receptor (EGFR) kinase with IC50 of 0.86 μM. Less active than the (-) enantiomer.

Specs

Chinese alias	酪氨酸磷酸化抑制剂AG 835 \| (S)-N-(α-甲基苯甲基)-3,4-二羟基苯亚甲基氰基乙酰胺 \| (S)-2-氰基-3-(3,4-二羟苯基)-N-(1-苯乙基)丙烯酰胺 \| (S)-(E)-2-氰基-3-(3',4'-二羟基苯基)-N-(1-苯乙基)-2-丙烯酰胺
English alias	Lopac-T-4443 \| Lopac-T-5568 \| Tox21_501198 \| (2E)-2-Cyano-3-(3,4-Dihydroxyphenyl)-N-[(1S)-1-Phenylethyl]-2-Propenamide \| (S,E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(1-phenylethyl)acrylamide \| Tyrphostin B50 \| KBio2_002893 \| (E)-2-cyano-3-(3,4-dihydroxyphenyl
CAS number	133550-37-5	molecular formula	C18H16N2O3
molecular weight	308.34 g/mol	Exact mass	≥98%
PSA	93.400 Å²	logp	2.700

numbering system

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physicochemical properties

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Safety information

pictogram：

GHS08

Signal word：

Warning

Hazard Statement：

H373: 通过长时间或反复暴露对器官造成损害 H371: 可能会损坏器官

Statement of Preventive Measures：

P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P308+P316: 如果暴露或担心：立即寻求紧急医疗救助。 P319: 如果你感到不适，请寻求医疗帮助。