compound introduction
VX-809 (Lumacaftor)通过促进突变型CFTR(F508del-CFTR)的成熟，从而纠正常见于囊性纤维化的CFTR突变，EC50为0.1 μM。 VX-809 (Lumacaftor) acts to correct CFTR mutations common in cystic fibrosis by increasing mutant CFTR (F508del-CFTR) maturation,EC50 of 0.1 μM.
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VX-809 (Lumacaftor)
Dangerous GoodsCAS number：936727-05-8 molecular formula：C24H18F2N2O5
overview
Specs
| Chinese alias | VX-809（Lumacaftor） | ||
| English alias | 3-(6-(1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid | D10134 | MFCD16659051 | Lumacaftor(vx-809vx809) | VX809 | VX-809 | AC-23172 | MLS006011120 | DB09280 | Lumacaftor (USAN) | SCHEMBL3339392 | 3-(6-(1- | ||
| CAS number | 936727-05-8 | molecular formula | C24H18F2N2O5 |
| molecular weight | 452.41 g/mol | Exact mass | - |
| PSA | 97.800 Ų | logp | 4.4 |
numbering system
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physicochemical properties
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Safety information
pictogram：
GHS06 , GHS08 , GHS05 , GHS07
Signal word：
Danger
Hazard Statement：
H301: 吞咽会中毒 H318: 造成严重的眼睛损伤 H312: 皮肤接触有害 H372: 通过长时间或反复暴露对器官造成损害 H360: 可能损害生育力或未出生的孩子
Statement of Preventive Measures：
P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。 P330: 漱口 P203: 使用前，获取、阅读并遵守所有安全说明。 P264+P265:
Production methods and uses
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Related
upstream information
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downstream information
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MSDS
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