CAS number：142557-61-7 molecular formula：C13H15N5O3
A-484954 是真核延长因子 2 (eEF2) 的高度选择性抑制剂，其 IC50 值为 280 nM。 Application A-484954 has been used a selective and potent inhibitor to inhibit eEF2K (eukaryotic elongation factor 2 kinase), in order to check the enhancement of synaptic transmission in the stratum radiatum of the hippocampal CA1 region. It has also been used as an eEF2K inhibitor to monitor real-time luminescence of U2OS Arntl::dLUC cells.
| Chinese alias | 7-氨基-1-环丙基-3-乙基-1,2,3,4-四氢-2,4-二氧吡啶并[2,3-d]嘧啶-6-羧酰胺 | 7-氨基-1-环丙基-3-乙基-1,2,3,4-四氢-2,4-二氧代-吡啶 \ [2,3-d] 嘧啶-6-甲酰胺 | ||
| English alias | 7-amino-1-cyclopropyl-3-ethyl-2,4-dioxo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidine-6-carboxamide | A 484954 | HY-110096 | BCP28798 | Kinome_3822 | NCGC00370744-05 | A-484954;A484954 | EKI | 7-amino-1-cyclopropyl-3-ethyl-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]p | ||
| CAS number | 142557-61-7 | molecular formula | C13H15N5O3 |
| molecular weight | 289.29 g/mol | Exact mass | ≥98%(HPLC) |
| PSA | 123.000 Ų | logp | 0.100 |
No numbering system information yet
No physical and chemical property information yet
No production method and use information yet
No upstream information yet
No downstream information yet
