compound introduction
槲皮素-d3是槲皮素的同位素标记类似物，槲皮素是具有潜在抗癌特性的类黄酮。它充当线粒体ATPase和磷酸二酯酶的抑制剂。它抑制PI3激酶活性，并略微抑制PIP激酶活性。此外。槲皮素对癌细胞系具有抗增殖作用，并可以通过II型雌激素受体减少癌细胞的生长。它也已显示在细胞周期的G1晚期将人类白血病T细胞停滞。 Quercetin-d3 is the isotope labelled analogue of Quercetin , which is a flavonoid with possible anticancer properties. It acts as a mitochondrial ATPase and phosphodiesterase inhibitor. It Inhibits PI3-kinase activity and slightly inhibits PIP kinase activity. Furthermore. Quercetin has antiproliferative effects on cancer cell lines and can reduce cancer cell growth via type II estrogen receptors. It also has been shown to arrest human leukemic T cells in late G1 phase of the cell cycle.
