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FDL169

Dangerous Goods

CAS number：1628416-28-3    molecular formula：C27H23FN4O4

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overview

compound introduction

FDL169是CFTR校正剂，用于修复功能缺陷的CFTR蛋白。 产品应用 CFTR corrector 2是囊性纤维化跨膜电导调节因子 (CFTR) 的调节剂，来自专利US20140274933。用于治疗携带 F508del 突变的囊性纤维化患者。 Information FDL169 FDL169 is a CFTR corrector that is designed to fix and restore the function of the defective CFTR protein. Targets CFTR In vitro FDL169 has been shown to increase Phe508del CFTR cell-surface abundance.

Specs

Chinese alias-
English aliasSCHEMBL16048480 | SB18874 | US9682969, 22 | US9682969, 17 | UNII-49PN4S4FDH | 2-[7-ethoxy-4-(3-fluorophenyl)-1-oxo-1,2-dihydrophthalazin-2-yl]-N-methyl-N-(2-methyl-1,3-benzoxazol-6-yl)acetamide | BDBM160525 | 49PN4S4FDH | CFTR corrector 2? | 1628416-28-3
CAS number1628416-28-3molecular formulaC27H23FN4O4
molecular weight486.49 g/molExact mass10mM in DMSO
PSA88.200 Ųlogp3.87

numbering system

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physicochemical properties

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Safety information

pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。

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