介绍: JNJ-42165279 (JNJ-5279) 是一种 fatty acid amide hydrolase (FAAH) 的抑制剂,可抑制重组人和大鼠FAAH,对应的IC50值分别为70 nM和313 nM。 Information JNJ-42165279 JNJ-42165279 (JNJ-5279) is an inhibitor of fatty acid amide hydrolase (FAAH) that inhibits recombinant human and rat FAAH with IC50 of 70 nM and 313 nM, respectively. Targets recombinant human FAAH (Cell-free assay); recombinant rat FAAH (Cell-free assay) 70 nM; 313 nM
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JNJ-42165279
Dangerous GoodsCAS number:1346528-50-4 molecular formula:C18H17ClF2N4O3
overview
compound introduction
Specs
| Chinese alias | N-(4-氯-3-吡啶基)-4-[(2,2-二氟-1,3-苯并二恶茂-5-基)甲基]-1-哌嗪甲酰胺 | ||
| English alias | Tox21_302191 | 1346528-50-4 | US9688664, 1 | AH2E5UQ11Y | DTXSID501045937 | Example 1 [WO2011139951 A1] | SB19640 | 4-(2,2-difluoro-benzo[1,3]dioxol-5-ylmethyl)-piperazine-1-carboxylic acid (4-chloro-pyridin-3-yl)-amide | JNJ 42165279 | EX-A2790 | GTPL901 | ||
| CAS number | 1346528-50-4 | molecular formula | C18H17ClF2N4O3 |
| molecular weight | 410.8 g/mol | Exact mass | - |
| PSA | 66.900 Ų | logp | 4.009 |
numbering system
No numbering system information yet
physicochemical properties
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Safety information
pictogram:
GHS08 , GHS07
Signal word:
Warning
Hazard Statement:
H302: 吞食有害 H361: 怀疑破坏生育力或未出生的孩子 H361f: 怀疑破坏生育力
Statement of Preventive Measures:
P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P203: 使用前,获取、阅读并遵守所有安全说明。 P318: 如果暴露或担心,请就医。
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MSDS
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