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UNC1999

Dangerous Goods

CAS number:1431612-23-5    molecular formula:C33H43N7O2

overview

compound introduction

UNC1999是口服生物相容性的EZH2和EZH1抑制剂,IC50分别为2 nM和45 nM。 UNC1999 is a potent, orally bioavailable and selective inhibitor of EZH2 and EZH1 with IC50 of 2 nM and 45 nM in cell-free assays, respectively, showing >1000-fold selectivity over a broad range of epigenetic and non-epigenetic targets.

Specs

Chinese alias-
English aliasMFCD26960958 | HMS3653O13 | SCHEMBL16767552 | Q27089090 | UNC1999 | UNC-1999 | 1431612-23-5 | YSZC348 | DTXSID001099939 | N-[(6-methyl-2-oxo-4-propyl-1H-pyridin-3-yl)methyl]-1-propan-2-yl-6-[6-(4-propan-2-ylpiperazin-1-yl)pyridin-3-yl]indazole-4-carboxami
CAS number1431612-23-5molecular formulaC33H43N7O2
molecular weight569.74 g/molExact mass-
PSA95.400 Ųlogp4.800

numbering system

No numbering system information yet

physicochemical properties

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Safety information

pictogram:
GHS07
Signal word:
Warning
Hazard Statement:
H302: 吞食有害
Statement of Preventive Measures:
P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P330: 漱口 P301+P317: 如果被吞咽:请寻求医疗帮助。
WGK Germany:
3

Production methods and uses

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upstream information

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downstream information

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MSDS

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