compound introduction
TMS ((E)-2,3',4,5'-tetramethoxystilbene) 是一种选择性和竞争性 CYP1B1 抑制剂，IC50 为 6 nM，Ki 值为 3 nM。TMS 对 CYP1A1 (IC50=300 nM) 和 CYP1A2 (IC50=3.1 μM) 的抑制作用较小。TMS 是白藜芦醇的甲基化衍生物，具有抗癌活性。
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2,4,3′,5′-tetramethoxystilbene
Dangerous GoodsCAS number：24144-92-1 molecular formula：C18H20O4
overview
Specs
| Chinese alias | 2,4,3',5'-四甲氧基二苯乙烯 | (E)-1-(3,5-二甲氧基苯乙烯基)-2,4-二甲氧基苯 | ||
| English alias | AC-35369 | SR-01000597603 | NSC-748799 | Stilbene, 2,3',4,5'-tetramethoxy- | trans-2,4,3'',5''-tetramethoxystilbene | trans-2,4,3',5'-tetramethoxystilbene | Glycon S-80 | AS-71536 | Trans-2,3',4,5'-tetramethoxystilbene | (E)-4,5'-(ethene-1,2-diyl)bis(1,3- | ||
| CAS number | 24144-92-1 | molecular formula | C18H20O4 |
| molecular weight | 300.35 g/mol | Exact mass | ≥98%(HPLC) |
| PSA | 36.900 Ų | logp | 4.100 |
numbering system
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physicochemical properties
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Safety information
pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H302: 吞食有害
Statement of Preventive Measures：
P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P330: 漱口 P301+P317: 如果被吞咽：请寻求医疗帮助。
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MSDS
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