微囊藻毒素-LR属于环状七肽代谢产物微囊藻毒素类，由蓝绿藻铜绿微囊藻和其它藻类产生。 应用： 该分析标准品可用于以下应用：1.开发一种基于纳米生物碳（nBC）和抗微囊藻毒素-LR单克隆抗体（mAbs）的用于鉴定环境水样品中微囊藻毒素-LR的纸质免疫传感器；2.通过基于分子印迹聚合物和酶辅助颜色变化方法的侧流免疫色谱分析（LFICA）方法测定自来水样品中的微囊藻毒素-LR；3.采用单壁碳纳米管（SWNT）和dapoxyl 荧光染料制备的适体传感器进行自来水和血清样品中微囊藻毒素-LR的荧光检测；4.通过超高效液相色谱-质谱（UHPLC-MS）和高效液相色谱-可变波长紫外检测器方法（HPLC-VW-UVD）分析地表水样品以检测微囊藻毒素-LR；5.通过高效液相色谱和带电喷雾电离源的串联质谱（HPLC-ESI-MS/MS）测定地表水样品中的微囊藻毒素-LR。 Product introduction： Microcystins are toxic molecules produced by cyanobacterial blooms due to water eutrophication. Microcystin-LR proves to be a potent inhibitor of type 1 (IC50=1.7 nM) and type 2A (IC50= 0.04 nM) protein phosphatases. Microcystin-LR inhibits the activity of both type 1 and type 2A phosphatases >10-fold more potently than okadaic acid under the same conditions. Type 2A protein phosphatases in dilute mammalian cell extracts are found to be completely inhibited by 0.5 nM microcystin-LR while type 1 protein phosphatases are only slightly affected at this concentration. Application： Microcystin-LR may be used as an analytical reference standard for the determination of the analyte in surface water samples using high-performance liquid chromatography coupled to tandem mass spectrometry with electrospray ionization source (HPLC-ESI-MS/MS).
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Microcystin-LR (MCYST-LR)
Dangerous GoodsCAS number：101043-37-2 molecular formula：C49H74N10O12
overview
compound introduction
Specs
| Chinese alias | 生物毒素, 蓝藻毒素, 藻华毒素,快速死亡因子 | ||
| English alias | Cyanoginosin LR | Toxin-LR | Toxin I (Microcystis aeruginosa) | ||
| CAS number | 101043-37-2 | molecular formula | C49H74N10O12 |
| molecular weight | 995.17 g/mol | Exact mass | - |
| PSA | 343.000 Ų | logp | 2.300 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram：
GHS06 , GHS08 , GHS02
Signal word：
Danger
Hazard Statement：
H225: 高度易燃的液体和蒸气 H301+H331: 吞咽或吸入可致中毒。 H301+H311: 吞咽或皮肤接触可致中毒。
Statement of Preventive Measures：
P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P311: 打电话给毒物中心或医生。。。 P210: 远离热源，热表面，火花，明火和其他点火源。 - 禁止抽烟。 P302+P352: 如皮肤沾染：用水充分清洗。 P312: 打电话给毒物中心或医生。。。如果你觉得不舒服 P301+P330+P331: 如误吞咽：漱口。不要诱导呕吐。 P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。
WGK Germany：
WGK 2
Personal protective equipment：
Eyeshields, Faceshields, Gloves, multi-purpose combination respirator cartridge (US)
Production methods and uses
No production method and use information yet
Related
upstream information
No upstream information yet
downstream information
No downstream information yet
MSDS
Found 0 shareMSDS
