Azido-PEG2-C2-amine 是一种 PROTAC linker，属于 PEG 类，可用于合成 PROTAC 分子。Azido-PEG2-C2-amine 也是一种不可降解的含 2 个单元 PEG 的 ADC linker，可用于合成抗体偶联活性分子 (ADC)。Azido-PEG2-C2-amine 是一种点击化学试剂。它含有 Azide 基团，可以和含有 Alkyne 基团的分子发生铜催化的叠氮-炔环加成反应（CuAAc)。还可以和含有 DBCO 或 BCN 基团的分子发生菌株促进的炔-叠氮环加成反应 (SPAAC) Azido-PEG2-C2-amine is a PROTAC linker belonging to the PEG class that can be used to synthesize PROTAC molecules. Azido-PEG2-C2-amine is also a non-degradable 2-unit PEG ADC linker that can be used to synthesize antiboy-coupled active molecules (ADCs). Azido-PEG2-C2-amine is a click chemical agent. It contains Azide groups and can undergo copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing Alkyne groups. Strain-promoted acetylene-azide cycloaddition reactions (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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Azido-PEG2-amine
Dangerous GoodsCAS number：166388-57-4 molecular formula：C6H14N4O2
overview
compound introduction
Specs
| Chinese alias | 2-[2-(2-叠氮乙氧基)乙氧基]乙胺 | 2-(2-(2-叠氮乙氧基)乙氧基)乙胺 | ||
| English alias | ZB0975 | Azido-PEG2-C2-amine | Azido-PEG2-Amine | HY-140213 | 2-(2-(2-azidoethoxy)ethoxy)ethanamine | GS-5982 | SCHEMBL13612332 | 2-[2-(2-AZIDOETHOXY)ETHOXY]ETHANAMINE | AB69528 | AMY4540 | MFCD13189985 | N3-PEG2-CH2CH2NH2 | 2-[2-(2-Azidoethoxy)ethoxy]eth | ||
| CAS number | 166388-57-4 | molecular formula | C6H14N4O2 |
| molecular weight | 174.20 g/mol | Exact mass | ≥98% |
| PSA | 58.800 Ų | logp | -0.100 |
numbering system
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physicochemical properties
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Safety information
pictogram：
GHS05
Signal word：
Danger
Hazard Statement：
H314: 造成严重的皮肤灼伤和眼睛损伤
Statement of Preventive Measures：
P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P301+P330+P331: 如误吞咽：漱口。不要诱导呕吐。 P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。 P363: 再次使用之前，请清洗受污染的衣物。 P305+P354+P338: 如果进入眼睛：立即用水冲洗几分钟
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MSDS
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