GW 9578是有效激活PPARα的激动剂,其EC | 50 |值分别为0.005和0.05μM,可激活鼠类和人类受体。与PPARγ和PPARβ相比,GW 9578对PPARα的选择性高。GW 9578是有效的降脂剂。 GW 9578 is a potent agonist of PPARα that activates the murine and human receptors with EC|50|values of 0.005 and 0.05 μM, respectively. GW 9578 is highly selective for PPARα compared to PPARγ and PPARβ. GW 9578 is a potent lipid lowering agent.
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GW 9578
Dangerous GoodsCAS number:247923-29-1 molecular formula:C26H34F2N2O3S
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| Chinese alias | - | ||
| English alias | J-015674 | H32ABL87X4 | GW 9578 | AKOS040748513 | DTXSID10179493 | UNII-H32ABL87X4 | GTPL2673 | 2-[4-[2-[(2,4-difluorophenyl)carbamoyl-heptylamino]ethyl]phenyl]sulfanyl-2-methylpropanoic acid | GSK9578 | Q27077961 | 2- [[4- [2- [[[(2, 4- difluorophenyl)am | ||
| CAS number | 247923-29-1 | molecular formula | C26H34F2N2O3S |
| molecular weight | 492.6 g/mol | Exact mass | - |
| PSA | 94.900 Ų | logp | 6.800 |
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Safety information
UN Number:
1231
Packing Group:
II
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