RP-64477

Dangerous Goods

CAS number：135239-65-5 molecular formula：C29H42N2O3S

overview

Specs

numbering system

physicochemical properties

Safety information

Production methods and uses

MSDS

overview

compound introduction

Information RP-64477 RP-64477 is a potent inhibitor of the cholesterol esterifying enzyme Acyl-coenzyme A:cholesterol O-acyltransferase (ACAT) . RP-64477 inhibits ACAT activity with IC50 of 113 nM, 503 nM, and 180 nM in human intestinal (CaCo-2), hepatic (HepG2) and monocytic (THP-1) cell assays, respectively. Targets ACAT (CaCo-2 cell-based assay); ACAT (THP-1 cell-based assay); ACAT (HepG2 cell-based assay) 113 nM; 180 nM; 503 nM

Specs

Chinese alias	-
English alias	UNII-K10EML8B3S \| Benzamide, n-butyl-3-((4-(decyloxy)benzoyl)amino)-4-(methylthio)- \| MS-29261 \| N'-Butyl-4-(decyloxy)-4'-(methylthio)-N,3'-bibenzamide \| K10EML8B3S \| N-butyl-3-(4-(decyloxy)benzamido)-4-(methylthio)benzamide \| N-butyl-3-(p-decyloxybenzami
CAS number	135239-65-5	molecular formula	C29H42N2O3S
molecular weight	498.72 g/mol	Exact mass	10mM in DMSO
PSA	92.700 Å²	logp	7.742

numbering system

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physicochemical properties

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Safety information

pictogram：

GHS07

Signal word：

Warning

Hazard Statement：

H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H302: 吞食有害

Statement of Preventive Measures：

P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P301+P312: 如误吞咽：如感觉不适，呼叫急救中心/医生。