Levosalbutamol酒石酸盐(levalbuterol)是短效β2肾上腺素受体激动剂salbutamol的R型对映体。 Information Levalbuterol tartrate Levalbuterol HCl is a relatively selective beta2-adrenergic receptor agonist used for the treatment of asthma. In vivo Racemic albuterol (7.5 mg, bid) results in a greater improvement in their forced expiratory volume in 1 second (FEV1) as well as in their asthma scores after 1 hour of continuous treatment compared to the Levalbuterol (3.75 mg, bid) administration in children with asthma. The greater improvement in asthma scores is maintained after the second hour of continuous therapy in the racemic albuterol group but not for forced expiratory volume in 1 second (FEV1) measurements. Levalbuterol (1.25 mg) requires significantly fewer median total nebulizations and scheduled nebulizations compared with those in the racemic albuterol (2.5 mg) group in patients with asthma or chronic obstructive pulmonary disease (COPD). Disease symptom assessment and subject general well-being score scores improves significantly from baseline in both levalbuterol (1.25 mg) and racemic albuterol (2.5 mg) treatment groups, and beta-mediated adverse effects mean scores are significantly greater with levalbuterol versus racemic albuterol.
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Levalbuterol tartrate
Dangerous GoodsCAS number:661464-94-4 molecular formula:C30H48N2O12
overview
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Specs
| Chinese alias | - | ||
| English alias | (R)-4-(2-(tert-Butylamino)-1-hydroxyethyl)-2-(hydroxymethyl)phenol (2R,3R)-2,3-dihydroxysuccinate | (R)-4-(2-(tert-Butylamino)-1-hydroxyethyl)-2-(hydroxy-methyl)phenol (2R,3R)-2,3-dihydroxysuccinate | (R)-4-(2-(tert-butylamino)-1-hydroxyethyl)-2-(hydroxym | ||
| CAS number | 661464-94-4 | molecular formula | C30H48N2O12 |
| molecular weight | 628.71 g/mol | Exact mass | 10mM in DMSO |
| PSA | - | logp | - |
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physicochemical properties
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Safety information
pictogram:
GHS07
Signal word:
Warning
Hazard Statement:
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激
Statement of Preventive Measures:
P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染:用水充分清洗。 P321: 特殊处理(请参阅此标签上的...)。 P264: 处理后要彻底洗手。 P362+P364: 脱掉沾污的衣服,清洗后方可重新使用。 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P337+P317: 如果眼睛刺激持续:寻求医疗帮助。 P332+P317:
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