Vortioxetine (Lu AA21004) is a multimodal serotonergic agent, inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT with IC50 of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively. IC50 Value: 15nM (5-HT1A); 33nM (5-HT1B); 3.7nM(5-HT3A); 19nM (5-HT7); 1.6 nM(SERT) Target: 5-HT receptor Vortioxetine (Lu AA21004) is a multimodal serotonergic agent, inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT with IC50 of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively. IC50 Value: 15nM (5-HT1A); 33nM (5-HT1B); 3.7nM(5-HT3A); 19nM (5-HT7); 1.6 nM(SERT) Target: 5-HT receptor
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Vortioxetine
Dangerous GoodsCAS number:508233-74-7 molecular formula:C18H22N2S
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | Lu AA 21004 | AR-270/43507985 | GG-0052 | Lu AA 21004 | Piperazine, 1-[2-[(2,4-dimethylphenyl)thio]phenyl]-; 1-[2-(2,4-Dimethylphenylsulfanyl)phenyl]piperazine; Lu AA 21004; Vortioxetine | VORTIOXETINE [INN] | FS-3517 | 1-[2-(2,4-dimethylphenylsulfanyl)ph | ||
| CAS number | 508233-74-7 | molecular formula | C18H22N2S |
| molecular weight | 298.45 g/mol | Exact mass | - |
| PSA | 40.600 Ų | logp | 4.200 |
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physicochemical properties
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Safety information
pictogram:
GHS08
Signal word:
Warning
Hazard Statement:
H373: 通过长时间或反复暴露对器官造成损害 H361: 怀疑破坏生育力或未出生的孩子 H371: 可能会损坏器官
Statement of Preventive Measures:
P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P203: 使用前,获取、阅读并遵守所有安全说明。 P318: 如果暴露或担心,请就医。 P308+P316: 如果暴露或担心:立即寻求紧急医疗救助。 P319: 如果你感到不适,请寻求医疗帮助。
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