AM404

Dangerous Goods

CAS number：183718-77-6 molecular formula：C26H37NO2

overview

Specs

numbering system

physicochemical properties

Safety information

Production methods and uses

MSDS

overview

compound introduction

AM404 是一种内源性大麻素再摄取抑制剂，可阻断 anandamide 转运，IC50 值在低微摩尔范围。去氧肾上腺素使大鼠离体肝动脉收缩，AM404 可使其放松，pEC50 值为 7.4 (对应的 EC50 值为 0.04 µM)。具有神经保护作用。 AM404, an inhibitor of endocannabinoid reuptake, blocks anandamide transport with IC50 values in the low micromolar range. AM404 is able to relax rat isolated hepatic arteries contracted with Phenylephrine, with a pEC50 value of 7.4 (corresponding to an EC50 of 0.04 µM). Neuroprotective Effect.

Specs

Chinese alias	AM-404 \| N-arachidonoylaminophenol
English alias	am404 \| AM-404 \| CPD000449274 \| Q4652517 \| N-(4-hydroxyphenyl)-eicosa-5,8,11,14-tetraenamide \| CHEBI:197140 \| STK760084 \| DC34415 \| AM 404 \| NC00006 \| HMS2051K03 \| Tocris-1116 \| UNII-XVJ94H0U21 \| (5Z,8Z)-Icosa-5,8,11,14-tetraenoic acid (4-hydroxy-phenyl)-
CAS number	183718-77-6	molecular formula	C26H37NO2
molecular weight	395.58 g/mol	Exact mass	-
PSA	49.300 Å²	logp	7.200

numbering system

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physicochemical properties

No physical and chemical property information yet

Safety information

pictogram：

GHS02

Signal word：

Danger

Hazard Statement：

H225: 高度易燃的液体和蒸气

Statement of Preventive Measures：

P210: 远离热源，热表面，火花，明火和其他点火源。 - 禁止抽烟。

WGK Germany：

Personal protective equipment：

Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter