Mozavaptan hydrochloride (OPC-31260 hydrochloride) 是一种 benzazepine 衍生物,也是一种有效,选择性,竞争性和口服活性的加压素 V2 受体拮抗剂,IC50 为 14 nM。Mozavaptan hydrochloride 对 V2 受体的选择性比 V1 受体 (IC50 为 1.2 μM) 高约 85 倍,并且可以在体内拮抗精氨酸加压素的抗利尿作用。Mozavaptan hydrochloride 可用于低钠血症,抗利尿激素不适当综合征 (SIADH) 和充血性心力衰竭的研究。
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OPC 31260 hydrochloride
Dangerous GoodsCAS number:138470-70-9 molecular formula:C27H30ClN3O2
overview
compound introduction
Specs
| Chinese alias | 盐酸莫扎伐普坦 | ||
| English alias | 5-(Dimethylamino)-1-[4-(2-methylbenzamido)benzoyl]-2,3,4,5-tetrahydro-1H-benzazepine hydrochloride | mozavaptan HCl | Mozavaptan hydrochloride | N-(4-(5-(Dimethylamino)-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)phenyl)-2-methylbenzamide hydrochlori | ||
| CAS number | 138470-70-9 | molecular formula | C27H30ClN3O2 |
| molecular weight | 464.00 g/mol | Exact mass | ≥98% |
| PSA | 52.700 Ų | logp | - |
numbering system
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physicochemical properties
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Safety information
pictogram:
GHS07
Signal word:
Warning
Hazard Statement:
H302: 吞食有害
Statement of Preventive Measures:
P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P330: 漱口 P301+P317: 如果被吞咽:请寻求医疗帮助。
WGK Germany:
3
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MSDS
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