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Product introduction
辛可卡因是一种一元羧酸酰胺,是2-丁氧基喹啉-4-甲酸的2-(二乙氨基)乙酰胺。作为长效局部麻醉药中最有效和有毒的药物之一,其注射使用仅限于脊髓麻醉。现在通常(通常作为盐酸辛可卡因)用于乳膏和软膏,以及用于栓剂,暂时缓解与皮肤和肛门直肠状况相关的疼痛和瘙痒。它具有局部麻醉剂的作用。它是一种一元羧酸酰胺、芳香醚和三级胺化合物。
Chinese name
地布卡因
English name
2-butoxy-N-[2-(diethylamino)ethyl]quinoline-4-carboxamide
Chinese alias
狄布卡因,辛可卡因
English alias
Cincainum | Cinchocaine | Cinchocaine [INN] | D04AB02 | DIBUCAINE (USP IMPURITY) | Dibucaine 1% | Cinchocaine(Dibucaine) | DIBUCAINE [MI] | MFCD00047595 | NSC 159055 | Cinchoninamide, 2-butoxy-N-(2-(diethylamino)ethyl)- | Spectrum3_000384 | 2-Butoxy-quino
CAS number
85-79-0
molecular formula
C20H29N3O2
molecular weight
343.5
Exact mass
分析标准品
PSA
54.5
Logp
4.4
Safety
  • Disposal method: SRP:在审查时,土地处理或填埋(卫生填埋)处置实践的标准正在重大修订中。在实施废物残渣(包括废物污泥)的土地处置之前,咨询环境监管机构以获取可接受的处置实践指导。
  • Regulatory information: 新西兰化学品清单状态:辛可卡因:没有单独批准,但可在适当的团体标准下使用
  • interaction: 通过降低吸收速率,/肾上腺素/不仅能使麻醉剂集中在所需部位,还能使其在体内的破坏速率与吸收到血液循环中的速率保持同步。这降低了其全身毒性。/局部麻醉剂/
  • Human toxicity extract: 一名2岁儿童显然摄入了地布卡因盐酸盐(0.5%纽帕卡因霜),行为异常,蹒跚,然后抽搐,发绀,呕吐,发生心肺骤停并死亡。/地布卡因盐酸盐/
  • Other safety information: 化学品评估:IMAP评估 - 4-喹甲酰胺,2-丁氧基-N-[2-(二乙氨基)乙基]-:人类健康I级评估
  • non-human toxicity value: LD50 兔子静脉注射 2500 ug/kg
  • Hazard categories and classifications: 眼睛损伤 1 (95.1%)
  • Effects During Pregnancy and Lactation: ◉ 对哺乳和母乳的影响
Technical Documents
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upstream information
Manufacturing method:
盐酸丁卡因(CID:521951)
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Research chemical ≥98. 0%; 100mg

Research chemical ≥98. 0%; 100mg; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: ≥98. 0%; 100mg.

item number:710059
Product model:100mg
level: ≥98. 0%; 100mg
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