
- Treatment: 目前尚无已知的多环芳烃解毒剂。暴露通常通过症状治疗处理。(L10)
- Hazard summary: 眼睛、皮肤和呼吸道的刺激物;如果吞咽、吸入或通过皮肤吸收可能有害;[MSDSonline] 受到冲击可能爆炸;[Hawley] 参见多环芳烃。
- exposure pathway: 口服(L10);吸入(L10)
- Toxicity summary: 多环芳烃(PAH)与血液蛋白(如白蛋白)结合的能力使它们能够在体内运输。许多多环芳烃通过与芳烃受体或甘氨酸N-甲基转移酶蛋白结合,诱导细胞色素P450酶(特别是CYP1A1、CYP1A2和CYP1B1)的表达。这些酶将多环芳烃代谢为其毒性中间体。多环芳烃的反应性代谢物(环氧化物中间体、二氢二醇、酚类、醌及其各种组合)共价结合到DNA和其他细胞大分子上,引发突变和致癌。(L10, L23, A27, A32)
- Regulatory information: 澳大利亚工业化学品清单:化学物质:萘并蒽
- Health Effects: 多环芳烃是致癌物,已被证实会增加皮肤、呼吸道、膀胱、胃和肾脏癌症的风险。它们还可能导致生殖效应并抑制免疫系统。(L10)
- Symptoms and Signs: 急性暴露于多环芳烃会导致皮肤和肺组织刺激和炎症。(A10)
- Hazard categories and classifications: 水生慢性1 (80%)
- Carcinogen Classification: IARC未列出。IARC已评估相关PAHs (L2154)。
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Research chemical ≥97. 0%; 100mg
Research chemical ≥97. 0%; 100mg; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: ≥97. 0%; 100mg.




