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Product introduction
氯唑西林是一种半合成青霉素抗生素,在6位带有3-(2-氯苯基)-5-甲基异噁唑-4-甲酰胺基团。它具有抗菌剂和抗菌药物的作用。它是一种青霉素、半合成衍生物和青霉素过敏原。它与苯唑西林功能相关。它是氯唑西林(1-)的共轭酸。
Chinese name
邻氟苯唑青霉素
English name
(2S,5R,6R)-6-[[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Chinese alias
-
English alias
[3-(o-chlorophenyl)-5-methyl-4-isoxazolyl]penicillin; 3-dimethyl-7-oxo-thyl-4-isoxazolecarboxamido)-; 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylicacid,6-(3-(o-chlorophenyl)-5-me; 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylicacid,6-(3-(o-chlorophenyl)-s
CAS number
61-72-3
molecular formula
C19H18ClN3O5S
molecular weight
435.9
Exact mass
-
PSA
138
Logp
2.4
Safety
  • Storage conditions: 市售的氯唑西林钠胶囊和口服溶液粉末应储存在密封容器中,温度低于40°C,最好在15-30°C之间。重新配制后,氯唑西林钠口服溶液应储存在2-8°C,任何未使用的溶液应在14天后丢弃。如果在室温下储存,口服溶液可稳定3天。/氯唑西林钠/
  • Disposal method: SRP:在审查时,土地处理或填埋(卫生填埋)处置实践的标准正在重大修订中。在实施废物残渣(包括废物污泥)的土地处置之前,咨询环境监管机构以获取可接受的处置实践指导。
  • Other safety information: 化学品评估:IMAP评估 - 4-硫杂-1-氮杂双环[3.2.0]庚烷-2-甲酸,6-[[[3-(2-氯苯基)-5-甲基-4-异噁唑基]羰基]氨基]-3,3-二甲基-7-氧代-,[2S-(2α,5α,6β)]-:人类健康I级评估
  • non-human toxicity value: LD50 小鼠口服 5.0 G/KG
  • Allowable Tolerances: 规定牛未煮熟的可食用组织和牛奶中氯唑西林的残留容许量为0.01 ppm。
  • Hazard categories and classifications: STOT SE 3 (85.4%)
  • Non-human toxic extract: 单次口服剂量后6-18小时,猫和狗出现呼吸衰竭死亡,伴或不伴惊厥。急性胃肠炎和心血管性休克...豚鼠也是如此,除了晚期...逐渐发展的毒血症杀死了所有急性反应的幸存者。/青霉素类/
  • Antidote and first aid: 4. 吸收预防:A. 除非患者昏迷、惊厥或失去咽反射,否则应催吐。B. ...在进行大口径管胃灌洗前应先进行气管插管。C. 活性炭...D. 硫酸钠或硫酸镁...作为泻药.../青霉素类/
  • Drug Induced Liver Injury: 参考文献:DOI:10.1016/j.drudis.2019.09.022
  • Effects During Pregnancy and Lactation: 截至修订日期,未找到相关已发表信息。
Technical Documents
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Related
upstream information
Manufacturing method:
6-氨基青霉烷酸(CID:11082);氯唑西林(CID:6098);氯唑西林钠(CID:23675320)
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Research chemical 100mg

Research chemical 100mg; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 100mg.

item number:722097-100mg
Product model:100mg
level: 100mg
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