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Product introduction
醋丁洛尔是一种醚,是3-(丙-2-基氨基)丙烷-1,2-二醇的伯羟基与2-乙酰-4-(丁酰氨基)苯基形成的醚。它具有拟交感神经药、β-肾上腺素能拮抗剂、降压药和抗心律失常药的作用。它是乙醇胺、醚、单羧酸酰胺、丙醇胺、仲胺化合物和芳香酰胺的成员。它是醋丁洛尔(1+)的共轭碱。
Chinese name
acebutolol, β 1-肾上腺素受体拮抗剂
English name
N-[3-acetyl-4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]butanamide
Chinese alias
醋丁洛尔
English alias
A935714 | N-(3-acetyl-4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)phenyl)butanamide | N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]butanamide | SBI-0051584.P003 | 1-(2-Acetyl-4-n-butyramidophenoxy)-2-hydroxy-3-isopropylaminopropane | B
CAS number
37517-30-9
molecular formula
C18H28N2O4
molecular weight
336.4
Exact mass
-
PSA
87.7
Logp
1.7
Safety
  • Hepatotoxicity: 可能性评分:C(可能是明显肝损伤的原因)。
  • Primary Hazards: 未分类
  • Other safety information: 化学品评估:IMAP评估 - 丁酰胺,N-[3-乙酰基-4-[2-羟基-3-[(1-甲基乙基)氨基]丙氧基]苯基]-,(.+-.)-:人类健康一级评估
  • Hazard categories and classifications: 乳糖(100%)
  • Drug Induced Liver Injury: 参考文献:DOI:10.1016/j.drudis.2019.09.022
  • Effects During Pregnancy and Lactation: 截至修订日期,未找到关于正常哺乳期间β-阻滞或醋丁洛洛效应的相关已发表信息。一项对6名高催乳素血症和溢乳患者的研究发现,使用普萘洛尔进行β-肾上腺素能阻滞后,血清催乳素水平没有变化。
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Research chemical 1mg

Research chemical 1mg; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 1mg.

item number:726872-1mg
Product model:1mg
level: 1mg
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