(S)-Ibuprofen is the active enantiomer of ibuprofen. (S)-Ibuprofen inhibits Cox-1 and Cox-2 with comparable potency (ID50 = 8.9-14 μM and 7.2-8.2 μM, respectively). (S)-Ibuprofen acts as a non-steroidal analgesic and antiinflammatory agent. This compound’s inhibition of Cox-1 and Cox-2 and activation of PPARα and PPARγ isoforms may be responsible for its pharmacological effects.用于药代动力学研究的抗炎药布洛芬的对映体。 (S)-Ibuprofen is the active enantiomer of ibuprofen. (S)-Ibuprofen inhibits Cox-1 and Cox-2 with comparable potency (ID50 = 8.9-14 μM and 7.2-8.2 μM, respectively). (S)-Ibuprofen acts as a non-steroidal analgesic and antiinflammatory agent. This compound’s inhibition of Cox-1 and Cox-2 and activation of PPARα and PPARγ isoforms may be responsible for its pharmacological effects. (S)-(+)-Ibuprofen is the enantiomer associated with the anti-inflammatory action of ibuprofen, which is widely used as a nonsteroidal anti-inflammatory drug in racemic form. Enantiomeric form of the anti-inflammatory agent ibuprofen used in pharmacokinetic studies.