
- Hazard summary: 一种刺激物;[Sigma-Aldrich MSDS] 参见喹啉。
- Harmful effect: 新型喹诺酮类药物存在大量严重不良事件报告,其中一些已导致这些药物从美国市场撤回。这些包括QTc间期延长、肝毒性、血糖异常、神经病变、肾病、眼毒性、主动脉瘤/夹层、主动脉和二尖瓣反流、光毒性、血液毒性、免疫效应和重症肌无力加重。中枢神经系统相关的不良反应如意识模糊、虚弱、头痛、焦虑、食欲不振、震颤或抑郁也特别值得关注,尤其是在老年人中,这些症状可能被误归因于其他疾病。
- Toxicity summary: 如果患者开始显示潜在的肌腱炎或肌腱断裂迹象,建议立即停止使用喹诺酮类药物并避免使用受影响的关节。这些迹象可能包括肌腱疼痛、肿胀或炎症。对于出现严重不良事件的情况,包括史蒂文斯-约翰逊综合征、中毒性表皮坏死松解症、肝毒性和过敏反应,也建议停止使用喹诺酮类药物并立即采取支持措施。
- Regulatory information: 新西兰EPA化学品状态清单:2(1H)-喹啉酮:没有单独批准,但可在适当的团体标准下使用
- ecotoxicity value: USDA APHIS化学品影响:collection=usda_chemeffect&query_type=synonym&query='^59-31-4$'
- Other safety information: 化学品评估:IMAP评估 - 2-喹啉醇:人类健康I级评估
- Hazard categories and classifications: 特定靶器官毒性-单次接触 3级 (98.7%)
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Research chemical ≥98. 0%; 250mg
Research chemical ≥98. 0%; 250mg; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: ≥98. 0%; 250mg.




