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Product introduction

T-2 Toxin (T-2 Mycotoxin) 是饲料和谷物中的各种镰刀菌种产生的真菌毒素。小大鼠中T-2 Toxin 的 LD50 值分别为 5.2 和1.5 mg/kg BWa。T-2 Toxin (T-2 Mycotoxin) 可以转化为多种代谢产物，动物中T-2 Toxin 的典型代谢产物是 HT-2 toxin 和 T-2-triol，均为水解产物。 T-2 Toxin (T-2 Mycotoxin) 是一种抑制肽基转移酶 (60s ribosomal 亚基) 结合和蛋白质合成的抑制剂，抑制 DNA 和 RNA 的合成，干扰膜磷脂的代谢，并增加肝脏脂质过氧化物的水平。 T-2 Toxin (T-2 Mycotoxin) 在免疫系统，胃肠道组织和胎儿组织中诱导细胞凋亡 apoptosis。

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Chinese name

T-2 毒素

English name

T-2 Toxin

Chinese alias

T-2 毒素 | 镰孢毒素 T 2 | 毒枝菌素 T 2 | 单端孢霉烯族毒素

English alias

Fusariotoxin T 2 | T-2 Mycotoxin | Mycotoxin T2 | Epoxytrichothecene

CAS number

21259-20-1

molecular formula

C24H34O9

molecular weight

466.52 g/mol

Exact mass

PSA

121.000 Å²

Logp

0.900

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