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Product introduction
萘丁美酮是一种甲基酮,是在2-丁酮的4号位的一个甲基氢被6-甲氧基-2-萘基取代。一种前体药物,口服给药后转化为活性代谢物6-甲氧基-2-萘基乙酸。研究表明,与大多数其他非甾体抗炎药物相比,其胃肠道副作用的风险略低。它具有非甯体抗炎药、非麻醉性镇痛药、前体药物和环氧合酶2抑制剂的作用。它是一种甲氧基萘和甲基酮。
Chinese name
萘丁美酮, 环氧化酶-2 抑制剂
English name
4-(6-methoxynaphthalen-2-yl)butan-2-one
Chinese alias
-
English alias
MFCD00079518 | 4-(6-methoxynaphthalen-2-yl)butan-2-one | BSPBio_000758 | Flambate | KBioGR_000687 | Spectrum_001486 | CCRIS 8108 | DivK1c_000850 | LW0TIW155Z | Nabumetone 750 mg | Tox21_110647_1 | HMS2093I05 | HMS502K12 | NABUMETONE [JAN] | s4051 | MLS000
CAS number
42924-53-8
molecular formula
C15H16O2
molecular weight
228.29
Exact mass
-
PSA
26.3
Logp
3.1
Safety
  • Hepatotoxicity: 可能性评分:E*(尚未证实但怀疑是引起明显肝损伤的罕见原因)。
  • Hazard categories and classifications: 水生慢性毒性 2 (14.3%)
  • Protective Action Standards (PAC): PAC-3: 66 [mg/m3]
  • Drug Induced Liver Injury: 参考文献:DOI:10.1016/j.drudis.2019.09.022
  • Effects During Pregnancy and Lactation: ◉ 对哺乳和母乳的影响
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Research chemical 1mL

Research chemical 1mL; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 1mL.

item number:92897a
Product model:1mL
level: 1mL
Lead Time:-
sold 438 Items
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