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Product introduction
肉碱是一种氨基乙酸,其丁酸在位置 C-3 被羟基取代,C-4 上有一个三甲基铵基团。它作为小鼠代谢物和人类代谢物发挥作用。它在功能上与丁酸盐相关。它是肉碱的共轭碱。
Chinese name
左旋肉碱
English name
3-hydroxy-4-(trimethylazaniumyl)butanoate
Chinese alias
肉毒碱,L-肉碱
English alias
L-Carnitin | LEVOCARNITINE (EP MONOGRAPH) | levocarnitine HCl | MFCD00038747 | L-(-)-Carnitine | 3-carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium | LEVOCARNITINE (USP-RS) | (-)-L-Carnitine | 1-Propanaminium, 3-carboxy-2-hydroxy-N,N,N-trimethyl-, hydrox
CAS number
541-15-1
molecular formula
C7H15NO3
molecular weight
161.20
Exact mass
分析标准品
PSA
60.4
Logp
-0.2
Safety
  • exposure pathway: 静脉注射、口服。绝对生物利用度为 15%(片剂或溶液)。达到最大血浆浓度的时间为 3.3 小时。
  • Toxicity summary: 左旋肉碱可在体内由氨基酸赖氨酸或甲硫氨酸合成。维生素 C(抗坏血酸)对肉碱的合成至关重要。左旋肉碱是长链脂肪酸穿过线粒体内膜的载体分子。它还将酰基从细胞器中运出,并从细胞运至尿液之前积累到有毒浓度。只有 L-型肉碱(有时称为维生素 BT)影响脂质代谢。左旋肉碱由不同途径中的几种蛋白质处理,包括肉碱转运蛋白、肉碱易位酶、肉碱乙酰转移酶和肉碱棕榈酰转移酶。
  • Regulatory information: 新西兰 EPA 化学品状态清单:肌氨酸(Carnitine):没有单独的批准许可,但可以在适当的群体标准下使用。
  • Toxicity Data: LD<sub>50</sub> > 8g/kg(小鼠,口服)。
  • Symptoms and Signs: 不良反应包括高血压、发热、心动过速和抽搐。
  • Carcinogen Classification: 对人类无致癌性指示(未列入 IARC)。
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Research chemical 1mL

Research chemical 1mL; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 1mL.

item number:93187x
Product model:1mL
level: 1mL
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