Share to
Overview
Specs
Safety
Technical Documents
Related
Articles
reviews
Consult
returns
Product introduction
物理描述 | 甲苯磺丁脲呈白色晶体。(NTP,1992)
Chinese name
甲苯磺丁脲, 磺酰脲受体 1、Kir6.2 阻断剂
English name
1-butyl-3-(4-methylphenyl)sulfonylurea
Chinese alias
甲糖宁
English alias
NSC 23813 | Orinase | Tolylsulfonylbutylurea | CAS-64-77-7 | tolbutamide | U 2043 | 3-butyl-1-(4-methylbenzenesulfonyl)urea | DTXCID801359 | N-4-Methylbenzolsulfonyl-N-butylurea | SMR000058363 | Tolbutamida | Tolbutamidum [INN-Latin] | 1-p-Toluenesulfonyl
CAS number
64-77-7
molecular formula
C12H18N2O3S
molecular weight
270.35
Exact mass
-
PSA
83.7
Logp
2.3
Safety
  • Health hazard: 急性/慢性危害:加热分解时,该化合物会释放剧毒烟雾。(NTP, 1992)
  • reactive group: 磺酸盐、膦酸盐和硫代膦酸盐,有机
  • Disposal method: SRP:在审查时,土地处理或填埋(卫生填埋)处置实践的标准正在重大修订中。在实施废物残渣(包括废物污泥)的土地处置之前,咨询环境监管机构以获取可接受的处置实践指导。
  • First aid measures: 食入:不要催吐。如果受害者意识清醒且没有抽搐,给予1-2杯水稀释化学物质,并立即呼叫医院或中毒控制中心。如果医生建议,准备将受害者送往医院。如果受害者抽搐或昏迷,不要经口给予任何东西,确保受害者的气道通畅,让受害者侧卧,头部低于身体。不要催吐。立即将受害者送往医院。(NTP, 1992)
  • Regulatory information: 新西兰EPA化学品清单状态:甲苯磺丁脲:没有单独批准,但可在适当的团体标准下使用
  • fire hazard: 该化学品的闪点数据不可用。它可能是可燃的。(NTP, 1992)
  • fire fighting: 涉及此材料的火灾可以用干化学灭火器、二氧化碳或哈龙灭火器控制。(NTP, 1992)
  • Special Reports: NTP TR No 031;途径:口服饲料;物种:大鼠和小鼠。NTIS No PB274483/AS。[NTP;毒理学研究与测试部;管理状态报告;07/07/93;第27页]
  • reactivity profile: 甲苯磺丁脲是一种酰胺。酰胺/酰亚胺与偶氮和重氮化合物反应生成有毒气体。有机酰胺/酰亚胺与强还原剂反应形成易燃气体。酰胺是非常弱的碱(比水弱)。酰亚胺的碱性更弱,实际上会与强碱反应形成盐。也就是说,它们可以作为酸反应。将酰胺与脱水剂如P2O5或SOCl2混合会生成相应的腈。这些化合物的燃烧会生成氮的混合氧化物(NOx)。该化学品与酸不相容。(NTP, 1992)。
  • Human toxicity extract: 昏迷或精神状态改变通常是大多数(90%)摄入过量磺酰脲类药物患者最重要的表现症状.../磺酰脲/
  • Other safety information: 化学品评估:IMAP评估 - 苯磺酰胺,N-[(丁基氨基)羰基]-4-甲基-:环境I级评估
  • Air and water reaction: 不溶于水。
  • Hazard categories and classifications: 特定靶器官毒性-单次接触1级(14.3%)
  • Non-fire leakage response: 储存注意事项:您应将此材料存放在冰箱中。(NTP, 1992)
  • Personal protective equipment (PPE): 推荐呼吸器:在称量和稀释纯测试化学品时,佩戴NIOSH批准的半面罩呼吸器,配备有机蒸气/酸性气体 cartridges(专门用于有机蒸气、HCl、酸性气体和SO2)和粉尘/雾过滤器。(NTP,1992)
  • Carcinogen Classification: 总结:在本生物测定条件下,甲苯磺丁脲对Fischer 344大鼠和B6C3F1小鼠均无致癌性。
  • Drug Induced Liver Injury: 参考文献:DOI:10.1016/j.drudis.2019.09.022
  • Effects During Pregnancy and Lactation: ◉ 对哺乳和母乳的影响
Related
upstream information
Manufacturing method:
异丁基异氰酸酯 (CID:8110)
Articles
「No related articles yet」
user reviews
Loading...
Consultation

Warm reminder:

Because the manufacturer may temporarily adjust product specifications, prices, inventory, parameters and other information without notice, and there are differences in each user's consultation time and procurement needs, the platform reply content is only of reference value within a certain period. Sorry for the inconvenience caused to you, and thank you for your understanding and support! Please consult the online customer service for the latest details. Everything is subject to the real-time reply of the customer service.!

After Sales Services

Please check the quantity, appearance and product information in time when you receive the goods. In case of damage, wrong delivery, abnormal quality and other problems, please feel free to contact us.

Service Hotline:400-6226-992 ,We will handle it for you as soon as possible, thank you for your support and trust.!

Research chemical 1. 2mL

Research chemical 1. 2mL; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 1. 2mL.

item number:94846a
Product model:1.2mL
level: 1. 2mL
Lead Time:-
sold 321 Items
Ask Solution engineer
Qty

Recommended for you