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Product introduction
阿洛司琼是一种在2-位具有5-甲基-1H-咪唑-4-基甲基基团的吡啶并[4,3-b]吲哚化合物。它作为血清素拮抗剂、止吐药和胃肠道药物发挥作用。它是咪唑类和吡啶吲哚类的一员。
Chinese name
阿洛司琼
English name
5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-3,4-dihydropyrido[4,3-b]indol-1-one
Chinese alias
-
English alias
ALOSETRON; ALOSETRON 2,3,4,5-Tetrahydro-5-methyl-2-((5-methyl-1H-imidazol-4-yl)methyl)-1H-pyrido(4,3-b)indol-1-one
CAS number
122852-42-0
molecular formula
C17H18N4O
molecular weight
294.35
Exact mass
-
PSA
53.9
Logp
1.6
Safety
  • Harmful effect: CYP3A4抑制剂:酮康唑、克拉霉素、泰利霉素、伏立康唑、伊曲康唑和蛋白酶抑制剂是强效CYP3A4抑制剂,可能增加阿洛司琼的毒性。由于潜在的药物相互作用,临床医生在同时给予阿洛司琼和CYP3A4抑制剂时应谨慎。
  • Toxicity summary: 阿洛司琼没有特定的解毒剂。患者应接受适当的支持治疗。阿洛司琼过量可能降低其他药物的首过代谢。过量治疗方案应联系中毒控制中心。
  • Drug Induced Liver Injury: 参考文献:DOI:10.1016/j.drudis.2019.09.022
  • Effects During Pregnancy and Lactation: ◉ 对哺乳和母乳的影响
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Research chemical 10mg

Research chemical 10mg; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 10mg.

item number:A125218-10mg
Product model:10mg
level: 10mg
Lead Time:-
sold 724 Items
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