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名称
醛缩酶 来源于兔肌肉(悬浮液)
别名
二磷酸果糖酶 | D-果糖-1,6-二磷酸-D-甘油醛-3-磷酸裂解酶
英文别名
D-Fructose-1,6-bisphosphate-D-glyceraldehyde-3-phosphate-lyase | Fructose-diphosphate Aldolase | fructose-bisphosphate aldolase | fructose-1,6-bisphosphate triosephosphate-lyase | ALDOA | ALDOB | ALDB
货号
A128741-100mg
包装规格
100mg
级别
EnzymoPure™
浓度
≥10 units/mg protein, 10-45 mg protein/mL
产品介绍
兔醛缩酶存在三种亚型,包括来自肌肉的A型、肝脏B型和大脑相关C型。醛缩酶分子量为158 kDa,以四聚体形成存在。 醛缩酶可用于将果糖1,6-二磷酸转化为磷酸二羟丙酮和3-磷酸甘油醛。来自兔肌肉中的醛缩酶已被用于DHAP C3的立体特异性去质子化。 包装单位: 蛋白的质量。 产品应用 1、在标准兔肌肉来源1-磷酸果糖激酶 (RPFK-1)实验中使用 2、作为青光眼组织来源代谢酶测定的标准品 3、用于人细胞系的果糖2,6-二磷酸分析 Aldolase catalyzes a key reaction in glycolysis and energy production. Aldolase is used to convert fructose 1,6-diphosphate to dihydroxyacetone phosphate and glyceraldehyde 3-phosphate. Aldolase, from rabbit muscle has been used for stereospecific deprotonation at DHAP C3
生化机理
ALDO: Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein. ALDOB: Catalyzes the aldol cleavage of fructose 1,6-biphosphate to form two triosephosphates dihydroxyacetone phosphate and D-glyceraldehyde 3-phosphate in glycolysis as well as the reverse stereospecific aldol addition reaction in gluconeogenesis. In fructolysis, metabolizes fructose 1-phosphate derived from the phosphorylation of dietary fructose by fructokinase into dihydroxyacetone phosphate and D-glyceraldehyde (By similarity). Acts as an adapter independently of its enzymatic activity, exerts a tumor suppressor role by stabilizing the ternary complex with G6PD and TP53 to inhibit G6PD activity and keep oxidative pentose phosphate metabolism in check (By similarity).
生物活性
≥10 U/mg protein
来源
天然
预测分子量
158 kDa
种属
兔(Rabbit)
Safety
「No Dangerous Attributes」
Related
「No upstream and downstream information yet」
Technical Documents
「No technical documents」
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aldehyde (liquid) 100mg

item number:A128741-100mg
Product model:100mg
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Lead Time:30days
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