氨基 PEG, mPEG-NH2

甲氧基聚乙二醇胺 | O-(2-氨基乙基)-O′-甲基聚乙二醇 | 氨基聚乙二醇单甲醚 | 甲氧基聚氧乙烯胺

Methoxypolyethylene glycol amine | Methoxypolyoxyethylene amine | Aminopolyethylene glycol monomethyl ether | O-(2-Aminoethyl)-O′-methylpolyethylene glycol

Amino PEG, mPEG-NH2

A163269-1g

1g

MW 750 Da

-20°C储存,充氩

超低温冰袋运输

对空气敏感 对光敏感 对湿度敏感

甲氧基聚乙二醇胺可以： 形成树枝状胶束，增强疏水性化合物的溶解性。 与抗癌药物甲氨蝶呤（MTX）共轭形成 MTX-PEG，一种潜在的药物载体。 与聚乙烯亚胺（PEI）形成接枝共聚物，一种潜在的非病毒基因载体。 Amino functionalized methoxyl polyethylene glycol, amino PEG (mPEG-NH2) is a mono reactive PEG derivative that can be used to modify proteins, peptides and other materials via carboxylic group (-COOH) or other amine reactive chemical groups. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces. Application： Methoxypolyethylene glycol amine can: Form dendritic micelles to enhance the solubility of hydrophobic compounds. Conjugate with an anticancer drug methotrexate (MTX) to form MTX-PEG with potential application as drug carriers. Couple with polyethylenimine (PEI) to form graft copolymers which can be used as nonviral gene vectors.

H2NCH2CH2(OCH2CH2)nOCH3

80506-64-5

Off-white/white solid or viscous liquid depends on molecule weight;Soluble in regular aqeous solution as well as most organic solvents;