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名称

Ac-DEVD-AMC

别名

N-乙酰基-Asp-Glu-Val-Asp-7-酰胺基-4-甲基香豆素

英文别名

AC-ASP-MET-GLN-ASP-AMC, AC-ASP-MET-GLN-ASP-7-AMINO-4-METHYLCOUMARIN

货号

A378562-100mg

包装规格

100mg

浓度

≥97%

产品介绍

Ac-DEVD-AMC 是一种 caspase-3/caspase-7 荧光底物。用细胞裂解物处理 Ac-DEVD-AMC 时，Ac-DEVD-AMC 会释放氨基-4-甲基香豆素 (AMC) 用于荧光检测，激发波长为 380 nm，发射波长为 460 nm。用途： N-乙酰基-Asp-Glu-Val-Asp-7-酰胺基-4-甲基香豆素已被用作人结肠癌细胞系]和骨髓间充质干细胞中caspase-3检测的底物。 Ac-YEVD-AMCis a fluorogenic substrate for caspase-1 that is a cysteine protease activator of inflammatory processes which may be detected using a varie Application： N-Acetyl-Asp-Glu-Val-Asp-7-amido-4-methylcoumarin has been used as a substrate for caspase-3 assay in human colon cancer cell line and in bone marrow mesenchymal stem cells.

生化机理

caspase 3的荧光底物，而caspase 3是一种当细胞暴露于凋亡条件下时会被快速激活并裂解聚（ADP-核糖）聚合酶的蛋白酶。

Reaxy-Rn

29673793

序列

Ac-Tyr-Glu-Val-Asp-AMC

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

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「No technical documents」

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