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Product introduction

装运温度为4°C。储存在-20℃。存放在干燥的条件下。 A-1331852是一种有效的、选择性的BCL-XL抑制剂，对Bcl-xL的Ki值小于0.01 nM，对Bcl-2, Bcl-W, MCL-1的Ki值分别为6 nM, 4 nM, 142 nM。它可能在治疗癌症、免疫和自体免疫疾病中有所作用。 Shipped at 4°C. Store at -20°C. Store under desiccating conditions.

Specs ⸢ View details ⸥

Chinese name

A-1331852,BCL-XL抑制剂, Bcl-2-like 1 抑制剂

English name

A-1331852

Chinese alias

6-[8-[(2-苯并噻唑基氨基)羰基]-3,4-二氢-2(1H)-异喹啉基]-3-[5-甲基-1-(三环[3.3.1.13,7]dec-1-基甲基)-1H-吡唑-4-基]-2-吡啶甲酸

English alias

6-[8-[(2-benzothiazolylamino)carbonyl]-3,4-dihydro-2(1H)-isoquinolinyl]-3-[5-methyl-1-(tricyclo[3.3.1.13,7]dec-1-ylmethyl)-1H-pyrazol-4-yl]-2-pyridinecarboxylicacid | 3-(1-(adamantan-1-ylmethyl)-5-methyl-1H-pyrazol-4-yl)-6-(8-(benzo[d]thiazol-2-ylcarbamoy

CAS number

1430844-80-6

molecular formula

C38H38N6O3S

molecular weight

658.81 g/mol

Exact mass

PSA

141.000 Å²

Logp

7.500

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