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Product introduction
N3-PEG4-C2-Pfp ester 是一种不可降解的含 4 个单元 PEG 的 linker,可用于合成抗体偶联活性分子 (ADC) 。N3-PEG4-C2-Pfp ester 是一种点击化学试剂。它含有 Azide 基团,可以和含有 Alkyne 基团的分子发生铜催化的叠氮-炔环加成反应(CuAAc)。还可以和含有 DBCO 或 BCN 基团的分子发生菌株促进的炔-叠氮环加成反应 (SPAAC) Azido-PEG4-PFP ester is a PEG derivative containing an azide group and a PFP group. The azide group enables Click Chemistry. The PFP ester is a better leaving group compared to a hydroxyl group and can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The hydrophilic PEG spacer adds to the water solubility of this reagent. N3-PEG4-C2-Pfp ester is a non-degradable 4-unit PEG linker that can be used to synthesize antiboy-coupled active molecules (ADCs). N3-PEG4-C2-Pfp ester is a click chemical. It contains Azide groups and can undergo copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing Alkyne groups. Strain-promoted acetylene-azide cycloaddition reactions (SPAAC) can also occur with molecules containing DBCO or BCN groups. Application: Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.
Chinese name
叠氮基-PEG4-五氟苯酚酯
English name
Azido-PEG4-PFP ester
Chinese alias
-
English alias
N3-PEG4-C2-Pfp ester
CAS number
1353012-00-6
molecular formula
C17H20F5N3O6
molecular weight
457.35 g/mol
Exact mass
≥95%
PSA
77.600 Ų
Logp
2.400
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Research chemical 100mg; ≥95%

Research chemical 100mg; ≥95%; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 100mg; ≥95%.

item number:A595037-100mg
Product model:100mg
level: 100mg; ≥95%
Lead Time:30days
sold 917 Items
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100mg

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