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Product introduction

Azido-PEG4-(CH2)3OH 是一种 PROTAC linker，属于 PEG 类，可用于合成 PROTAC 分子。Azido-PEG4-(CH2)3OH 是一种点击化学试剂。它含有 Azide 基团，可以和含有 Alkyne 基团的分子发生铜催化的叠氮-炔环加成反应（CuAAc)。它还可以和含有 DBCO 或 BCN 基团的分子发生环张力驱动的炔-叠氮环加成反应 (SPAAC)。 Azido-PEG4-(CH2)3OH is a PEG derivative containing an azide group and a terminal hydroxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.

Specs ⸢ View details ⸥

Chinese name

叠氮基-PEG4-(CH2)3OH

English name

Azido-PEG4-(CH2)3OH

Chinese alias

1-叠氮-3,6,9,12-四氧杂十五烷-15-醇 | 叠氮-四聚乙二醇-丙醇

English alias

BP-23359 | 3-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]propan-1-ol | 2028281-87-8 | 1-azido-3,6,9,12-tetraoxapentadecan-15-ol | C70163 | DTXSID001258266 | BS-33865 | N3-PEG4-CH2CH2CH2OH | HY-140809 | AKOS040741250 | 4,7,10,13-Tetraoxapentadecan-1-ol, 1

CAS number

2028281-87-8

molecular formula

C11H23N3O5

molecular weight

277.32 g/mol

Exact mass

≥95%

PSA

71.500 Å²

Logp

0.2

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