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Product introduction

ABBV-CLS-484 是一种具有亚纳摩尔活性的有效的PTPN2抑制剂，具有抗肿瘤活性，可增强T细胞抗肿瘤免疫力。ABBV-CLS-484可用于治疗肿瘤、食管癌和消化系统疾病 ABBV-CLS-484 is a potent PTPN2 inhibitor with subnanomolar activity and antitumor activity that enhances T-cell anti-tumor immunity.ABBV-CLS-484 can be used for the treatment of neoplasms, esophageal cancer, and digestive disorders

Specs ⸢ View details ⸥

Chinese name

ABBV-CLS-484

English name

ABBV-CLS-484

Chinese alias

English alias

1,2,5-Thiadiazolidin-3-one, 5-((7R)-1-fluoro-5,6,7,8-tetrahydro-3-hydroxy-7-((3-methylbutyl)amino)-2-naphthalenyl)-, 1,1-dioxide | F89382 | GTPL11968 | 5-{(7R)-1-fluoro-3-hydroxy-7-[(3-methylbutyl)amino]-5,6,7,8-tetrahydronaphthalen-2-yl}-1lambda~6~,2,5-t

CAS number

2489404-97-7

molecular formula

C17H24FN3O4S

molecular weight

385.45 g/mol

Exact mass

PSA

107.000 Å²

Logp

2.100

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