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Product details

名称

AN3199

分子类型

小分子

英文名称

AN3199

货号

A648289-5mg

包装规格

5mg

浓度

≥99%

储存温度

-20°C储存

运输条件

超低温冰袋运输

产品介绍

AN3199 is a PDE4 inhibitor with an IC 50 of 94.5 nM. AN3199 can be used for the research of inflammation-associated diseases such as asthma and chronic obstructive pulmonary disease (COPD) In Vitro AN3199 (compound 11) (1 h) disappears (98.0%) is mainly converts to corresponding acid (76.6) in mouse plasma. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:PDE4 94.5 nM (IC 50 )

生化机理

AN3199 是一种 PDE4 抑制剂，IC50 为 94.5 nM。AN3199 可用于研究与炎症相关的疾病，如哮喘和慢性阻塞性肺病（COPD）。

CAS号

1187187-10-5

分子式

C17H18BNO5

分子量

327.14 g/mol

PubChem编号

46884349

Isomeric SMILES

B1(C2=C(CO1)C=C(C=C2)OC3=NC=C(C=C3)C(=O)OCCCC)O

IIUPAC Name

butyl 6-[(1-hydroxy-3H-2,1-benzoxaborol-5-yl)oxy]pyridine-3-carboxylate

INCHI

1S/C17H18BNO5/c1-2-3-8-22-17(20)12-4-7-16(19-10-12)24-14-5-6-15-13(9-14)11-23-18(15)21/h4-7,9-10,21H,2-3,8,11H2,1H3

InChi Key

BJXLLSAUQIAPDB-UHFFFAOYSA-N

Smiles

B1(C2=C(CO1)C=C(C=C2)OC3=NC=C(C=C3)C(=O)OCCCC)O

PubChem CID

46884349

溶解性

DMSO : 100 mg/mL (305.68 mM; Need ultrasonic)

氢键供体数Hydrogen Bond Donor Count

氢键受体数Hydrogen Bond Acceptor Count

可旋转键计数Rotatable Bond Count

精确质量Exact Mass

327.128 Da

单同位素质量Monoisotopic Mass

327.128 Da

拓扑极表面积Topological Polar Surface Area

77.900 Å²

重原子数Heavy Atom Count

形式电荷Formal Charge

复杂度Complexity

424.000

同位素原子数Isotope Atom Count

共价键合单元计数Covalently-Bonded Unit Count

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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