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名称

AKT Kinase Inhibitor

分子类型

小分子

别名

AKT 激酶抑制剂

英文名称

AKT Kinase Inhibitor

货号

A655267-1ml

包装规格

1ml

浓度

10mM in DMSO

储存温度

-80℃储存

运输条件

超低温冰袋运输

产品介绍

AKT Kinase Inhibitor is an Akt kinase inhibitor with anti-tumor activity. In Vitro The effect of selective inhibition of Akt in proliferating cells expressing Trop-2 is studied. Akt inhibition, either by silencing or with specific drugs, induces a marked decrease in cell proliferation in cells expressing Trop-2, in a dose-dependent fashion. MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo Trop-2 expressing tumors subcutaneously injected in animal models show a striking reduction of growth following treatment with specific drugs that inhibit Akt activity. Therefore Akt has a central functional role in mediating the Trop-2-dependent growth stimulus . MCE has not independently confirmed the accuracy of these methods. They are for reference only.

生化机理

AKT 激酶抑制剂是一种具有抗肿瘤活性的 Akt 激酶抑制剂。

CAS号

842148-40-7(DMSO)

分子式

C16H19N7O3

分子量

357.37 g/mol

Smiles

CCN1C2=C(C(=NC=C2OCCCN)C#CCO)N=C1C3=NON=C3N

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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