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Product introduction

AZD5423 is an inhaled, potent, selective, and non-steroidal glucocorticoid receptor (GR) modulator (SGRM) AZD5423 effectively reduces allergen-induced responses in subjects with mild allergic asthma . In Vitro The affinity of AZD5423 to the glucocorticoid receptor is high with an IC 50 of 0.9 nM in a radioligand human glucocorticoid receptor assay, and selectivity towards other steroid hormone receptors is >900-fold. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:Glucocorticoid receptor

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Chinese name

AZD5423, 糖皮质激素受体调节剂

English name

AZD5423

Chinese alias

English alias

Q15408423 | DB12280 | 2,2,2-TRIFLUORO-N-((1R,2S)-1-(1-(4-FLUOROPHENYL)INDAZOL-5-YL)OXY-1-(3-METHOXYPHENYL)PROPAN-2-YL)ACETAMIDE | SCHEMBL524607 | 641H0Q518W | EX-A5022 | AKOS040741197 | 8W8 | AZD-5423 | HY-108243 | MS-29055 | 1034148-04-3 | AZD 5423 | DTX

CAS number

1034148-04-3

molecular formula

C25H21F4N3O3

molecular weight

487.45 g/mol

Exact mass

≥99%

PSA

65.400 Å²

Logp

5.7

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