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名称

ALX 40-4C Trifluoroacetate

别名

ALX 40-4C 三氟乙酸盐

英文名称

ALX 40-4C Trifluoroacetate

货号

A659408-5mg

包装规格

5mg

浓度

≥96%

储存温度

-20°C储存,干燥

运输条件

超低温冰袋运输

敏感性

对湿度敏感

产品介绍

ALX 40-4C Trifluoroacetate 是一种趋化因子受体 (CXCR4) 抑制剂，能够抑制 SDF-1 与 CXCR4 结合，Ki 值为 1 μM，具有抗 HIV-1 作用；ALX 40-4C Trifluoroacetate 同时为 APJ 受体拮抗剂，IC50 值为 2.9 μM。序列 Ac-{d-Arg}-{d-Arg}-{d-Arg}-{d-Arg}-{d-Arg}-{d-Arg}-{d-Arg}-{d-Arg}-{d-Arg}-NH2 ALX 40-4C Trifluoroacetate is a small peptide inhibitor of the chemokine receptor CXCR4, inhibits SDF-1 from binding CXCR4 with a Ki of 1 μM, and suppresses the replication of X4 strains of HIV-1; ALX 40-4C Trifluoroacetate also acts as an antagonist of the APJ receptor, with an IC50 of 2.9 μM.

CAS号

143413-49-4(free)

分子式

C56H113N37O10(free)

分子量

1464.74(free) g/mol

溶解性

H2O : 50 mg/mL (31.67 mM; Need ultrasonic)

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

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