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Product introduction

AVJ16 是一种癌细胞迁徙抑制剂，靶向胰岛素样生长因子 2 mRNA 结合蛋白 IGF2BP1，可抑制高表达内源性 IGF2BP1 的 H1299 细胞迁移。AVJ16 可干扰 IGF2BP1 结合靶标 mRNA 以调节基因表达和翻译。 AVJ16 is a cancer cell migration inhibitor that targets the insulin-like growth factor 2 mRNA binding protein IGF2BP1 to inhibit the migration of H1299 cells with high endogenous IGF2BP1 expression. AVJ16 interferes with IGF2BP1 binding target mRNA to regulate gene expression and translation.

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Chinese name

AVJ16

English name

AVJ16

Chinese alias

(4-(苯并[d][1,3]二氧戊环-5-基)哌嗪-1-基)(4-((2-(羟甲基)-1H-吲哚-1-基)甲基)苯基)甲酮

English alias

(4-(Benzo[d][1,3]dioxol-5-yl)piperazin-1-yl)(4-((2-(hydroxymethyl)-1H-indol-1-yl)methyl)phenyl)methanone

CAS number

2775241-92-2

molecular formula

C28H27N3O4

molecular weight

469.53 g/mol

Exact mass

PSA

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